=== Backups ===
Have at least two copies(backups) of wallet.dat in two different locations, use dedicated USB sticks, that are marked clearly.
Do not use these USB stick for anything else, and keep them safe. Get good known named brand USB sticks, this is not the place to save cost.
Use different USB sticks for Hot wallet and Cold wallet backups. Especially cold wallet backup should not be plugged into a networked computer.